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The result of such channels on neuron firing amount in nigral dopamine neurons is these that administration of the KATP-channel antagonist glibenclamide in a 100 nM focus was equipped to improve neuron firing rate by 34% (Garcia de Arriba et al 1999; Avshalumov et al 2005). KATP-channel action also appears to get elevated by extracellular adenosine… Read More